Zfhx3^tm1.1Jtd
Targeted Allele Detail

Summary

• Symbol: Zfhx3^tm1.1Jtd
• Name: zinc finger homeobox 3; targeted mutation 1.1, Jin-Tang Dong
• MGI ID: MGI:5446504
• Synonyms: Atbf1^flox
• Gene: Zfhx3 Location: Chr8:109005975-109688272 bp, + strand Genetic Position: Chr8, 56.02 cM, cytoband E1
• Alliance: Zfhx3^tm1.1Jtd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189563
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 7. A FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 8. Flp-mediated recombination removed the neo cassette and left exons 7 and 8 floxed. (J:189563)

Generation of the Zfhx3^tm1.1Jtd allele

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Tumor Data

List all tumor models in MMHCdb carrying Zfhx3^tm1.1Jtd

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zfhx3 Mutation: 130 strains or lines available

References

• Original: J:189563 Sun X, et al., Heterozygous deletion of Atbf1 by the Cre-loxP system in mice causes preweaning mortality. Genesis. 2012 Nov;50(11):819-27
• All: 10 reference(s)