Il23r^tm1.2Trin
Targeted Allele Detail

Summary

• Symbol: Il23r^tm1.2Trin
• Name: interleukin 23 receptor; targeted mutation 1.2, Giorgio Trinchieri
• MGI ID: MGI:5446610
• Gene: Il23r Location: Chr6:67399916-67468839 bp, - strand Genetic Position: Chr6, 30.85 cM
• Alliance: Il23r^tm1.2Trin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189226
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the neo cassettes, exon 2 and exon 3. (J:189226)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il23r Mutation: 69 strains or lines available

References

• Original: J:189226 Grivennikov SI, et al., Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature. 2012 Nov 8;491(7423):254-8
• All: 2 reference(s)