Gpr26^tm1Yugs
Targeted Allele Detail

Summary

• Symbol: Gpr26^tm1Yugs
• Name: G protein-coupled receptor 26; targeted mutation 1, Yuguang Shi
• MGI ID: MGI:5446723
• Gene: Gpr26 Location: Chr7:131567891-131587362 bp, + strand Genetic Position: Chr7, 75.28 cM
• Alliance: Gpr26^tm1Yugs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189617
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exon 1 was replaced with a neo cassette via homologous recombination. (J:189617)

Generation of the Gpr26^tm1Yugs allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr26 Mutation: 27 strains or lines available

References

• Original: J:189617 Chen D, et al., Targeted inactivation of GPR26 leads to hyperphagia and adiposity by activating AMPK in the hypothalamus. PLoS One. 2012;7(7):e40764
• All: 1 reference(s)