Serpinb3a^tm1Gsil
Targeted Allele Detail

Summary

• Symbol: Serpinb3a^tm1Gsil
• Name: serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; targeted mutation 1, Gary A Silverman
• MGI ID: MGI:5447741
• Gene: Serpinb3a Location: Chr1:106973317-106980033 bp, - strand Genetic Position: Chr1, 50.34 cM
• Alliance: Serpinb3a^tm1Gsil page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:189949
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector containing a NEO cassette replaced most of exon 8. RT-PCR confirmed the absence of transcript expression. (J:189949)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Serpinb3a Mutation: 29 strains or lines available

References

• Original: J:189949 Sivaprasad U, et al., A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma. J Allergy Clin Immunol. 2011 Jan;127(1):254-61, 261.e1-6
• All: 3 reference(s)