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Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli
Transgene Detail
Summary
Symbol: Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli
Name: transgene insertion, Jack A Elias
MGI ID: MGI:5447949
Synonyms: Chit1 Tg
Transgene: Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli  Location: unknown  
Alliance: Tg(Scgb1a1-rtTA,tetO-CHIT1)#Eli page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Transactivator)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe mouse promoter drives lung-specific expression of the tetracycline reverse transactivator (rtTA), and the tetracycline promoter element drives inducible expression of the human cDNA. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:189872)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:189872 Lee CG, et al., Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-beta1 signaling. J Immunol. 2012 Sep 1;189(5):2635-44
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory