Nabp2^tm1.1Nfel
Targeted Allele Detail

Summary

• Symbol: Nabp2^tm1.1Nfel
• Name: nucleic acid binding protein 2; targeted mutation 1.1, Niklas Feldhahn
• MGI ID: MGI:5448641
• Synonyms: Obfc2b^lox
• Gene: Nabp2 Location: Chr10:128237264-128247361 bp, - strand Genetic Position: Chr10, 76.55 cM, cytoband D3
• Alliance: Nabp2^tm1.1Nfel page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190019
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of both exon 1 and after exon 2. Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of exon 2. (J:190019)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nabp2 Mutation: 16 strains or lines available

References

• Original: J:190019 Feldhahn N, et al., The hSSB1 orthologue Obfc2b is essential for skeletogenesis but dispensable for the DNA damage response in vivo. EMBO J. 2012 Oct 17;31(20):4045-56
• All: 2 reference(s)