Wwp1^tm1Lmat
Targeted Allele Detail

Summary

• Symbol: Wwp1^tm1Lmat
• Name: WW domain containing E3 ubiquitin protein ligase 1; targeted mutation 1, Lydia E Matesic
• MGI ID: MGI:5449071
• Gene: Wwp1 Location: Chr4:19608303-19708993 bp, - strand Genetic Position: Chr4, 7.56 cM
• Alliance: Wwp1^tm1Lmat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190204
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• A knock-out allele was generated. No details provided. (J:190204)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wwp1 Mutation: 64 strains or lines available

References

• Original: J:190204 Zhao L, et al., Tumor necrosis factor inhibits mesenchymal stem cell differentiation into osteoblasts via the ubiquitin E3 ligase Wwp1. Stem Cells. 2011 Oct;29(10):1601-10
• All: 4 reference(s)