Zfp281^tm1.1Jlwa
Targeted Allele Detail

Summary

• Symbol: Zfp281^tm1.1Jlwa
• Name: zinc finger protein 281; targeted mutation 1.1, Jianlong Wang
• MGI ID: MGI:5449148
• Gene: Zfp281 Location: Chr1:136552639-136557791 bp, + strand Genetic Position: Chr1, 59.93 cM
• Alliance: Zfp281^tm1.1Jlwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190201
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A floxed neo cassette replaced the entire gene. Cre-mediated recombination removed the neo cassette. (J:190201)

Expression

In Mice Carrying this Mutation:

6 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp281 Mutation: 27 strains or lines available

References

• Original: J:190201 Fidalgo M, et al., Zfp281 functions as a transcriptional repressor for pluripotency of mouse embryonic stem cells. Stem Cells. 2011 Nov;29(11):1705-16
• All: 3 reference(s)