Ccdc88a^tm4.1Mat
Targeted Allele Detail

Summary

• Symbol: Ccdc88a^tm4.1Mat
• Name: coiled coil domain containing 88A; targeted mutation 4.1, Masahide Takahashi
• MGI ID: MGI:5449207
• Gene: Ccdc88a Location: Chr11:29323658-29460808 bp, + strand Genetic Position: Chr11, 16.61 cM
• Alliance: Ccdc88a^tm4.1Mat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190129
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked pgk-neo cassette were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:190129)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ccdc88a Mutation: 76 strains or lines available

References

• Original: J:190129 Asai M, et al., Similar phenotypes of Girdin germ-line and conditional knockout mice indicate a crucial role for Girdin in the nestin lineage. Biochem Biophys Res Commun. 2012 Oct 5;426(4):533-8
• All: 4 reference(s)