Nuggc^tm1Diaz
Targeted Allele Detail

Summary

• Symbol: Nuggc^tm1Diaz
• Name: nuclear GTPase, germinal center associated; targeted mutation 1, Marilyn Diaz
• MGI ID: MGI:5449547
• Gene: Nuggc Location: Chr14:65835995-65885980 bp, + strand Genetic Position: Chr14, 34.34 cM
• Alliance: Nuggc^tm1Diaz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190402
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. A floxed neo cassette was inserted downstream of exon 4. (J:190402)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nuggc Mutation: 48 strains or lines available

References

• Original: J:190402 Richter K, et al., Altered pattern of immunoglobulin hypermutation in mice deficient in Slip-GC protein. J Biol Chem. 2012 Sep 14;287(38):31856-65
• All: 1 reference(s)