Enah^tm2.1Fbg
Targeted Allele Detail

Summary

• Symbol: Enah^tm2.1Fbg
• Name: ENAH actin regulator; targeted mutation 2.1, Frank B Gertler
• MGI ID: MGI:5449736
• Synonyms: Mena^FLOXED
• Gene: Enah Location: Chr1:181723949-181847555 bp, - strand Genetic Position: Chr1, 84.93 cM
• Alliance: Enah^tm2.1Fbg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190748
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 2 was floxed. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:190748)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enah Mutation: 208 strains or lines available

References

• Original: J:190748 Gupton SL, et al., Mena binds alpha5 integrin directly and modulates alpha5beta1 function. J Cell Biol. 2012 Aug 20;198(4):657-76
• All: 1 reference(s)