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Del(9Casp1-Casp4)1Bhk
Targeted Allele Detail
Summary
Symbol: Del(9Casp1-Casp4)1Bhk
Name: deletion, Chr 9, Beverly H Koller 1
MGI ID: MGI:5449892
Synonyms: Casp1/Casp4tm1Bhk, Del1Bhk
Gene: Del(9Casp1-Casp4)1Bhk  Location: unknown  Genetic Position: Chr9, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:189777
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion, Intragenic deletion
  Del(9Casp1-Casp4)1Bhk involves 2 genes/genome features (Casp1, Casp4) View all
 
Mutation detailsRecombination removed the entire coding regions of Casp1 and Casp4 along with 8 kb 5' of Casp1 and 6 kb 3' of Casp4. (J:189777)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(9Casp1-Casp4)1Bhk Mutation:  0 strains or lines available
References
Original:  J:189777 Kovarova M, et al., NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. J Immunol. 2012 Aug 15;189(4):2006-16
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory