Abcg1^tm1Tall
Targeted Allele Detail

Summary

• Symbol: Abcg1^tm1Tall
• Name: ATP binding cassette subfamily G member 1; targeted mutation 1, Alan Tall
• MGI ID: MGI:5450880
• Synonyms: Abcg1^fl
• Gene: Abcg1 Location: Chr17:31276668-31336958 bp, + strand Genetic Position: Chr17, 15.8 cM, cytoband A2-B
• Alliance: Abcg1^tm1Tall page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190966
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a single frt site and a single loxP site upstream of exon 3, and a loxP-flanked neomycin resistance (neo) cassette downstream of exon 3. (J:190966)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Abcg1 Mutation: 46 strains or lines available

References

• Original: J:190966 Westerterp M, et al., Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways. Cell Stem Cell. 2012 Aug 3;11(2):195-206
• All: 27 reference(s)