Del(13Simc1-B4galt7)2Dja
Targeted Allele Detail

Summary

• Symbol: Del(13Simc1-B4galt7)2Dja
• Name: deletion, Chr 13, David J Adams 2
• MGI ID: MGI:5451135
• Synonyms: Del2Dja, Df(13)Ms2Dja
• Gene: Del(13Simc1-B4galt7)2Dja Location: Chr13:54651592-55758256 bp Genetic Position: Chr13, Syntenic

Dilation of the renal pelvicalyceal system in Del(13Simc1-B4galt7)2Dja/+ mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190741
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted Mutations: Insertion, Intergenic deletion, Intragenic deletion Del(13Simc1-B4galt7)2Dja involves 55 genes/genome features (Gm17617, Gm19905, Simc1 ...) View all Mutation details: The deletion was generated by cre-mediated recombination between two MICER clones (MHPN55m07 and MHPP265c24) and removes a 1.5 Mb segment including 36 genes between Simc1 and B4galt7. (J:190741)

Generation of the Del(13Simc1-B4galt7)2Dja deletion

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(13Simc1-B4galt7)2Dja Mutation: 0 strains or lines available

References

• Original: J:190741 Migdalska AM, et al., Generation of the Sotos syndrome deletion in mice. Mamm Genome. 2012 Dec;23(11-12):749-57
• All: 1 reference(s)