Dock2^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Dock2^m3Btlr
• Name: dedicator of cyto-kinesis 2; mutation 3, Bruce Beutler
• MGI ID: MGI:5461202
• Synonyms: dew
• Gene: Dock2 Location: Chr11:34176815-34674719 bp, - strand Genetic Position: Chr11, 19.68 cM, cytoband A5
• Alliance: Dock2^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU-induced a C to T transversion that results in the amino acid substitution of a premature stop codon for glutamine at position 1439 (G1439X). (J:191187) Additional incidental mutations were detected in sequencing for the causative mutation, Dock2^m3Btlr, and may be present in stocks carrying this mutation.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dock2 Mutation: 143 strains or lines available

References

• Original: J:191187 Beutler B, Direct Data Submission. MGI Direct Data Submission. 2013;v
• All: 1 reference(s)