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Tada3tm1.1Viba
Targeted Allele Detail
Summary
Symbol: Tada3tm1.1Viba
Name: transcriptional adaptor 3; targeted mutation 1.1, Vimla Band
MGI ID: MGI:5462193
Synonyms: Ada3FL
Gene: Tada3  Location: Chr6:113343594-113354799 bp, - strand  Genetic Position: Chr6, 52.75 cM
Alliance: Tada3tm1.1Viba page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:190249
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neo cassette and left exons 2 through 4 floxed. (J:190249)
Generation of the Tada3tm1.1Viba allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tada3 Mutation:  31 strains or lines available
References
Original:  J:190249 Mohibi S, et al., Mammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression. J Biol Chem. 2012 Aug 24;287(35):29442-56
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory