Traf3ip2^tm2Sbn
Targeted Allele Detail

Summary

• Symbol: Traf3ip2^tm2Sbn
• Name: TRAF3 interacting protein 2; targeted mutation 2, Ulrich Siebenlist
• MGI ID: MGI:5462251
• Synonyms: Traf3ip2^fl
• Gene: Traf3ip2 Location: Chr10:39488930-39531303 bp, + strand Genetic Position: Chr10, 20.86 cM
• Alliance: Traf3ip2^tm2Sbn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191090
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was flanked by loxP sites. In addition a PGK/Neo cassette was flanked by FRT sites and was removed by crossing in a Flp recombinase that was then crossed out. (J:191090)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Traf3ip2 Mutation: 41 strains or lines available

References

• Original: J:191090 Pisitkun P, et al., Interleukin-17 cytokines are critical in development of fatal lupus glomerulonephritis. Immunity. 2012 Dec 14;37(6):1104-15
• All: 5 reference(s)