Ffar2^tm1Fmgb
Targeted Allele Detail

Summary

• Symbol: Ffar2^tm1Fmgb
• Name: free fatty acid receptor 2; targeted mutation 1, Fiona M Gribble
• MGI ID: MGI:5462347
• Gene: Ffar2 Location: Chr7:30517778-30523200 bp, - strand Genetic Position: Chr7, 19.25 cM
• Alliance: Ffar2^tm1Fmgb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191508
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• An IRES-lacZ and a floxed neo cassette replaced the coding sequence. (J:191508)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar2 Mutation: 25 strains or lines available

References

• Original: J:191508 Tolhurst G, et al., Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes. 2012 Feb;61(2):364-71
• All: 2 reference(s)