Tg(tetO-HMOX1)6Hyms
Transgene Detail

Summary

• Symbol: Tg(tetO-HMOX1)6Hyms
• Name: transgene insertion 6, Hyman M Schipper
• MGI ID: MGI:5462364
• Synonyms: TRE2.Flag.HMOX1
• Transgene: Tg(tetO-HMOX1)6Hyms Location: unknown
• Alliance: Tg(tetO-HMOX1)6Hyms page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-HMOX1)6Hyms expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HMOX1 (3162)

  Hmox1

  (MGI:96163)

• Mutation details: The tetracycline-responsive element and the minimal human cytomegalovirus (CMV) promoter drive the expression of a FLAG-tagged human HMOX1 coding sequence. The pound symbol (#) is used when a line is not specified and/or lines are pooled. (J:186620)

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:186620 Song W, et al., Schizophrenia-Like Features in Transgenic Mice Overexpressing Human HO-1 in the Astrocytic Compartment. J Neurosci. 2012 Aug 8;32(32):10841-10853
• All: 9 reference(s)