Tg(GFAP-tTA)6Hyms
Transgene Detail

Summary

• Symbol: Tg(GFAP-tTA)6Hyms
• Name: transgene insertion 6, Hyman M Schipper
• MGI ID: MGI:5462365
• Synonyms: GFAP.tTA
• Transgene: Tg(GFAP-tTA)6Hyms Location: unknown
• Alliance: Tg(GFAP-tTA)6Hyms page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: Expression of the tetracycline transactivator protein (containing the wild-type VP16 domain which allows for high tTA expression) is under the control of the glial fibrillary acidic protein promoter. (J:186620)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:186620 Song W, et al., Schizophrenia-Like Features in Transgenic Mice Overexpressing Human HO-1 in the Astrocytic Compartment. J Neurosci. 2012 Aug 8;32(32):10841-10853
• All: 8 reference(s)