Tg(CBS)11181Eri
Transgene Detail

Summary

• Symbol: Tg(CBS)11181Eri
• Name: transgene insertion 11181, Eleanor Roosevelt Institute
• MGI ID: MGI:5462465
• Synonyms: 60.4P102D1, TghCBS60.4
• Transgene: Tg(CBS)11181Eri Location: unknown
• Alliance: Tg(CBS)11181Eri page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CBS)11181Eri expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CBS (875)

  Cbs	(MGI:88285)

• Mutation details: This transgene consists of a 60.4 kbp DNA fragment isolated from the human P1 clone P102D1 containing only the human CBS gene (and approximately 50 kb of 5' upstream sequence). FISH analysis indicates that the human transgene integrated on a different chromosome from the mouse gene. (J:124730, J:165612)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:124730 Butler C, et al., The production of transgenic mice expressing human cystathionine beta-synthase to study Down syndrome. Behav Genet. 2006 May;36(3):429-38
• All: 8 reference(s)