Abcb6^tm1Pkr
Targeted Allele Detail

Summary

• Symbol: Abcb6^tm1Pkr
• Name: ATP-binding cassette, sub-family B member 6; targeted mutation 1, Partha Krishnamurthy
• MGI ID: MGI:5463225
• Gene: Abcb6 Location: Chr1:75148361-75157036 bp, - strand Genetic Position: Chr1, 38.62 cM, cytoband C3
• Alliance: Abcb6^tm1Pkr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190243
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3, 4, and 5 were replaced with a neo cassette via homologous recombination. (J:190243)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Abcb6 Mutation: 41 strains or lines available

References

• Original: J:190243 Chavan H, et al., Polycyclic aromatic hydrocarbons (PAHs) mediate transcriptional activation of the ATP binding cassette transporter ABCB6 gene via the aryl hydrocarbon receptor (AhR). J Biol Chem. 2012 Sep 14;287(38):32054-68
• All: 2 reference(s)