Kif19a^tm1Noh
Targeted Allele Detail

Summary

• Symbol: Kif19a^tm1Noh
• Name: kinesin family member 19A; targeted mutation 1, Nobutaka Hirokawa
• MGI ID: MGI:5463445
• Gene: Kif19a Location: Chr11:114656227-114681565 bp, + strand Genetic Position: Chr11, 80.44 cM
• Alliance: Kif19a^tm1Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191072
• Parent Cell Line: CMTI-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a pgk-betageo cassette via homologous recombination. Western blot analysis indicates loss of protein expression in oviducts and trachea from homozygous mice. (J:191072)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif19a Mutation: 40 strains or lines available

References

• Original: J:191072 Niwa S, et al., KIF19A Is a Microtubule-Depolymerizing Kinesin for Ciliary Length Control. Dev Cell. 2012 Dec 11;23(6):1167-75
• All: 1 reference(s)