Tg(Rp1)L2Eap
Transgene Detail

Summary

• Symbol: Tg(Rp1)L2Eap
• Name: transgene insertion L2, Eric A Pierce
• MGI ID: MGI:5463931
• Transgene: Tg(Rp1)L2Eap Location: unknown
• Alliance: Tg(Rp1)L2Eap page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Rp1)L2Eap expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Rp1 (MGI:1341105)

• Mutation details: A BAC clone containing 140 kb of mouse genomic DNA was used. An "EGFP-S-tag" was inserted into exon 2 at the N-terminus of the coding sequence. Three founder lines, L1, L2, and L3, were produced. Line L2 produced normal levels of gene product. (J:191685)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:191685 Liu Q, et al., Expression of wild-type Rp1 protein in Rp1 knock-in mice rescues the retinal degeneration phenotype. PLoS One. 2012;7(8):e43251
• All: 1 reference(s)