Atmin^tm1.2Jhh
Targeted Allele Detail

Summary

• Symbol: Atmin^tm1.2Jhh
• Name: ATM interactor; targeted mutation 1.2, Jorg Heierhorst
• MGI ID: MGI:5463937
• Synonyms: Asciz^fl
• Gene: Atmin Location: Chr8:117670132-117687184 bp, + strand Genetic Position: Chr8, 63.37 cM
• Alliance: Atmin^tm1.2Jhh page

Small spleen size in Atmin^tm1.2Jhh/Atmin^tm1.2Jhh/ Cd79a^tm1(cre)Reth/Cd79a⁺ mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191832
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon D, and an FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon D. Flp-mediated recombination removed the neo cassette and left exon D floxed. (J:191832)

Generation of the floxed Atmin^tm1.2Jhh allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Atmin Mutation: 38 strains or lines available

References

• Original: J:191832 Jurado S, et al., The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim. J Exp Med. 2012 Aug 27;209(9):1629-39
• All: 1 reference(s)