Htr1b^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Htr1b^{tm1.1(KOMP)Vlcg}
• Name: 5-hydroxytryptamine (serotonin) receptor 1B; targeted mutation 1.1, Velocigene
• MGI ID: MGI:5463939
• Gene: Htr1b Location: Chr9:81510344-81515881 bp, - strand Genetic Position: Chr9, 44.61 cM
• Alliance: Htr1b^{tm1.1(KOMP)Vlcg} page
• IMPC: Htr1b gene page

Mutation origin

• Mutant Cell Line: 13007A-F5
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 1237bp between positions 81524920-81526156 of Chromosome 9 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Htr1b Mutation: 26 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 6 reference(s)