Tg(MUT*R403X)#Hlps
Transgene Detail

Summary

• Symbol: Tg(MUT*R403X)#Hlps
• Name: transgene insertion, Heidi L Peters
• MGI ID: MGI:5464197
• Synonyms: MUT^stop+
• Transgene: Tg(MUT*R403X)#Hlps Location: unknown
• Alliance: Tg(MUT*R403X)#Hlps page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(MUT*R403X)#Hlps expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MMUT (4594)

  Mmut	(MGI:97239)

• Mutation details: The human BAC, RPCI-11-463L20, was modified (C to T in exon 6) to produce the amino acid substitution of a stop codon for arginine at position 403 (R403X). The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:191879)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:191879 Buck NE, et al., Development of transgenic mice containing an introduced stop codon on the human methylmalonyl-CoA mutase locus. PLoS One. 2012;7(9):e44974
• All: 1 reference(s)