Kxd1^tm1Wli
Targeted Allele Detail

Summary

• Symbol: Kxd1^tm1Wli
• Name: KxDL motif containing 1; targeted mutation 1, Wei Li
• MGI ID: MGI:5466155
• Gene: Kxd1 Location: Chr8:70966046-70975830 bp, - strand Genetic Position: Chr8, 34.15 cM
• Alliance: Kxd1^tm1Wli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192646
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exon 5. Western blot analysis confirmed the absence of protein expression in the testis, liver, kidney, intestine, spleen, lung, brain and skin. (J:192646)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kxd1 Mutation: 26 strains or lines available

References

• Original: J:192646 Yang Q, et al., The BLOS1-interacting protein KXD1 is involved in the biogenesis of lysosome-related organelles. Traffic. 2012 Aug;13(8):1160-9
• All: 3 reference(s)