Dp(1)22H
Chemically and radiation induced Allele Detail

Summary

• Symbol: Dp(1)22H
• Name: duplication, Chr 1, Harwell 22
• MGI ID: MGI:5466695
• Synonyms: Mut1171
• Gene: Dp(1)22H Location: unknown Genetic Position: Chr1, Syntenic

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Chemically and radiation induced
• Mutation: Duplication
• Mutation details: This mutation was identified among the progeny of a (C3H/HeH x 101/H)F1 male mouse that had received triethylenemelamine on day 1 and hydroxyurea (HU) and HU plus 6 Gy X-rays, at 3-hr intervals, on day 2 and later was mated to tester (PT) females. Cytogenetic analysis indicates that the duplication involves G-bands 1F and 1G and increases the length of Chr 1 by ~10%. The absence of quadrivalents at diakinesis of meiosis I in spermatocytes of an affected male confirms that the additional material is not derived from another chromosome. (J:192801)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dp(1)22H Mutation: 0 strains or lines available

References

• Original: J:192801 Cattanach BM, et al., A further large Chr 1 duplication. Mouse Genome. 1997;95(2):486
• All: 1 reference(s)