Sirt2tm1Gdon
Targeted Allele Detail
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| Symbol: |
Sirt2tm1Gdon |
| Name: |
sirtuin 2; targeted mutation 1, Gizem Donmez |
| MGI ID: |
MGI:5467245 |
| Gene: |
Sirt2 Location: Chr7:28466192-28488086 bp, + strand Genetic Position: Chr7, 16.92 cM, cytoband B1-2
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| Alliance: |
Sirt2tm1Gdon page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:193012
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: A puro cassette was inserted into exon 11. Western blot analysis confirmed the absence of all three protein isoforms in the brain.
(J:193012)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Sirt2 Mutation: |
27 strains or lines available
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| Original: |
J:193012 Bobrowska A, et al., SIRT2 ablation has no effect on tubulin acetylation in brain, cholesterol biosynthesis or the progression of Huntington's disease phenotypes in vivo. PLoS One. 2012;7(4):e34805 |
| All: |
5 reference(s) |
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Analysis Tools
