Mamld1^tm1Tsga
Targeted Allele Detail

Summary

• Symbol: Mamld1^tm1Tsga
• Name: mastermind-like domain containing 1; targeted mutation 1, Tsutomu Ogata
• MGI ID: MGI:5467328
• Gene: Mamld1 Location: ChrX:70093846-70199662 bp, + strand Genetic Position: ChrX, 36.33 cM
• Alliance: Mamld1^tm1Tsga page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192626
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neo cassette replaced exon 3. Western blot analysis confirmed the absence of protein expression. (J:192626)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mamld1 Mutation: 7 strains or lines available

References

• Original: J:192626 Miyado M, et al., Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40
• All: 2 reference(s)