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Pycardtm1Ayaz
Targeted Allele Detail
Summary
Symbol: Pycardtm1Ayaz
Name: PYD and CARD domain containing; targeted mutation 1, Amir S Yazdi
MGI ID: MGI:5467340
Synonyms: ASCf
Gene: Pycard  Location: Chr7:127590545-127593039 bp, - strand  Genetic Position: Chr7, 69.88 cM, cytoband F4
Alliance: Pycardtm1Ayaz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:191239
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. (J:191239)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pycard Mutation:  15 strains or lines available
References
Original:  J:191239 Drexler SK, et al., Tissue-specific opposing functions of the inflammasome adaptor ASC in the regulation of epithelial skin carcinogenesis. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18384-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory