Ric8a^tm1.1Zhua
Targeted Allele Detail

Summary

• Symbol: Ric8a^tm1.1Zhua
• Name: RIC8 guanine nucleotide exchange factor A; targeted mutation 1.1, Zhen Zhuang
• MGI ID: MGI:5467414
• Gene: Ric8a Location: Chr7:140437310-140443644 bp, + strand Genetic Position: Chr7, 86.06 cM
• Alliance: Ric8a^tm1.1Zhua page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191222
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 2 through 4 were floxed. Flp-mediated recombination removed the floxed neomycin resistance cassette. (J:191222, J:241849)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ric8a Mutation: 29 strains or lines available

References

• Original: J:191222 Ma S, et al., Ric-8a, a guanine nucleotide exchange factor for heterotrimeric G proteins, regulates bergmann glia-basement membrane adhesion during cerebellar foliation. J Neurosci. 2012 Oct 24;32(43):14979-93
• All: 3 reference(s)