Rdh13^tm1Xuxn
Targeted Allele Detail

Summary

• Symbol: Rdh13^tm1Xuxn
• Name: retinol dehydrogenase 13 (all-trans and 9-cis); targeted mutation 1, Xun Xu
• MGI ID: MGI:5467544
• Gene: Rdh13 Location: Chr7:4427769-4448648 bp, - strand Genetic Position: Chr7, 2.56 cM
• Alliance: Rdh13^tm1Xuxn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191615
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exons 2 and 3. Western blot analysis confirmed the absence of protein expression in the liver. (J:191615)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rdh13 Mutation: 13 strains or lines available

References

• Original: J:191615 Wang H, et al., Retinol dehydrogenase 13 protects the mouse retina from acute light damage. Mol Vis. 2012;18:1021-30
• All: 2 reference(s)