Wnt16^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Wnt16^tm1Lex
• Name: wingless-type MMTV integration site family, member 16; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:5467557
• Synonyms: Wnt16^-,exon1-3
• Gene: Wnt16 Location: Chr6:22288226-22298521 bp, + strand Genetic Position: Chr6, 9.22 cM, cytoband A3
• Alliance: Wnt16^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188156
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion A lacZ and floxed neo cassette replaced exons 1, 2 and 3. (J:188156, J:227247)

Generation of the Wnt16^tm1Lex allele

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt16 Mutation: 31 strains or lines available

References

• Original: J:188156 Zheng HF, et al., WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet. 2012 Jul;8(7):e1002745
• All: 4 reference(s)