Fam3c^tm1.1Lex
Targeted Allele Detail

Summary

• Symbol: Fam3c^tm1.1Lex
• Name: FAM3 metabolism regulating signaling molecule C; targeted mutation 1.1, Lexicon Genetics
• MGI ID: MGI:5467558
• Gene: Fam3c Location: Chr6:22306519-22356080 bp, - strand Genetic Position: Chr6, 9.24 cM
• Alliance: Fam3c^tm1.1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188156
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. Cre-mediated recombination removed the first two coding exons. (J:188156)

Generation of the Fam3c^tm1.1Lex allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam3c Mutation: 31 strains or lines available

References

• Original: J:188156 Zheng HF, et al., WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk. PLoS Genet. 2012 Jul;8(7):e1002745
• All: 1 reference(s)