Mirc15^tm1.2Czc
Targeted Allele Detail

Summary

• Symbol: Mirc15^tm1.2Czc
• Name: microRNA cluster 15, including Mir181a-2 through Mir181b-2; targeted mutation 1.2, Chang-Zheng Chen
• MGI ID: MGI:5467793
• Gene: Mirc15 Location: Chr2:38742747-38743930 bp Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:188125
• Parent Cell Line: CGR8 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the cluster. This allele lacks the neo selection cassette. (J:188125)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc15 Mutation: 2 strains or lines available

References

• Original: J:188125 Fragoso R, et al., Modulating the strength and threshold of NOTCH oncogenic signals by mir-181a-1/b-1. PLoS Genet. 2012 Aug;8(8):e1002855
• All: 1 reference(s)