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Cx3cr1tm1.1(cre)Jung
Targeted Allele Detail
Summary
Symbol: Cx3cr1tm1.1(cre)Jung
Name: C-X3-C motif chemokine receptor 1; targeted mutation 1.1, Steffen Jung
MGI ID: MGI:5467983
Synonyms: Cx3cr1cre
Gene: Cx3cr1  Location: Chr9:119877749-119897362 bp, - strand  Genetic Position: Chr9, 71.37 cM
Alliance: Cx3cr1tm1.1(cre)Jung page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:193038
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Cx3cr1tm1.1(cre)Jung expression driven by 1 gene
 
Mutation detailsA cre recombinase cassette with a floxed neo was introduced into a BAC by RedE/T recombineering, replacing the coding exon, prior to homologous recombination to target the gene in ES cells. Cre-mediated recombination removed the selection cassette. (J:193038)
Recombinase
activity
Activity:
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Driver: Cx3cr1 (mouse)
Summary of all recombinase alleles driven by Cx3cr1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cx3cr1 Mutation:  45 strains or lines available
References
Original:  J:193038 Yona S, et al., Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis. Immunity. 2013 Jan 24;38(1):79-91
All:  138 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory