Pnp^bata
Chemically induced Allele Detail

Summary

• Symbol: Pnp^bata
• Name: purine-nucleoside phosphorylase; bata
• MGI ID: MGI:5468722
• Synonyms: ENU8B5:058, ENU8B6:058 bata
• Gene: Pnp Location: Chr14:51181760-51190869 bp, + strand Genetic Position: Chr14, 26.31 cM, cytoband B-C1
• Alliance: Pnp^bata page

Mutation origin

• Strain of Origin: C57BL/6JSfdAnu
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This mutation was identified by IgM⁺ B-cell proliferation and flow cytometry screening of progeny of an ENU treated mouse. The mutation is an A to T substitution at nucleotide position 925 of the cDNA sequence (NCBI m37, Ensembl build 62), in a region corresponding to exon 5 of the gene. It results in replacement of aspartic acid by valine at amino acid position 215 of the protein. (J:104190)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pnp Mutation: 29 strains or lines available

References

• Original: J:104190 The Australian Phenomics Facility at The Australian National University, Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2006-2014
• All: 1 reference(s)