Fcnb^tm1Tefu
Targeted Allele Detail

Summary

• Symbol: Fcnb^tm1Tefu
• Name: ficolin B; targeted mutation 1, Teizo Fujita
• MGI ID: MGI:5468800
• Synonyms: Fcnb^tm1Yend
• Gene: Fcnb Location: Chr2:27966491-27974921 bp, - strand Genetic Position: Chr2, 19.38 cM, cytoband A3
• Alliance: Fcnb^tm1Tefu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:190858
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The promoter and exons1-4 were replaced with a neomycin resistance cassette. (J:190858)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fcnb Mutation: 23 strains or lines available

References

• Original: J:190858 Endo Y, et al., Mice Deficient in Ficolin, a Lectin Complement Pathway Recognition Molecule, Are Susceptible to Streptococcus pneumoniae Infection. J Immunol. 2012 Dec 15;189(12):5860-6
• All: 4 reference(s)