Wars2^{tm1.1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Wars2^{tm1.1(KOMP)Vlcg}
• Name: tryptophanyl tRNA synthetase 2 (mitochondrial); targeted mutation 1.1, Velocigene
• MGI ID: MGI:5468955
• Gene: Wars2 Location: Chr3:99047423-99128546 bp, + strand Genetic Position: Chr3, 43.03 cM, cytoband F3
• Alliance: Wars2^{tm1.1(KOMP)Vlcg} page
• IMPC: Wars2 gene page

Mutation origin

• Mutant Cell Line: 15335A-A7
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 46632bp between positions 98945025-98991656 of Chromosome 3 (Genome Build37) and subsequent cre expression excised the neomycin selection cassette. (J:136110, J:188991)

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wars2 Mutation: 22 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 5 reference(s)