Entpd7^tm1Ktak
Targeted Allele Detail

Summary

• Symbol: Entpd7^tm1Ktak
• Name: ectonucleoside triphosphate diphosphohydrolase 7; targeted mutation 1, Kiyoshi Takeda
• MGI ID: MGI:5469828
• Gene: Entpd7 Location: Chr19:43678111-43722136 bp, + strand Genetic Position: Chr19, 36.67 cM, cytoband D1
• Alliance: Entpd7^tm1Ktak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191188
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced part of exon 5 and all of exon 6. (J:191188)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Entpd7 Mutation: 32 strains or lines available

References

• Original: J:191188 Kusu T, et al., Ecto-Nucleoside Triphosphate Diphosphohydrolase 7 Controls Th17 Cell Responses through Regulation of Luminal ATP in the Small Intestine. J Immunol. 2013 Jan 15;190(2):774-83
• All: 1 reference(s)