Pilra^tm1Osb
Targeted Allele Detail

Summary

• Symbol: Pilra^tm1Osb
• Name: paired immunoglobin-like type 2 receptor alpha; targeted mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:5469884
• Synonyms: Pilra^tm1Maik
• Gene: Pilra Location: Chr5:137820214-137834540 bp, - strand Genetic Position: Chr5, 76.77 cM
• Alliance: Pilra^tm1Osb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191085
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exon 2. Western blot analysis confirmed the absence of protein expression in the spleen and bone marrow. (J:191085)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pilra Mutation: 25 strains or lines available

References

• Original: J:191085 Wang J, et al., Neutrophil infiltration during inflammation is regulated by PILRalpha via modulation of integrin activation. Nat Immunol. 2013 Jan;14(1):34-40
• All: 3 reference(s)