Fendrr^tm2Bgh
Targeted Allele Detail

Summary

• Symbol: Fendrr^tm2Bgh
• Name: Foxf1 adjacent non-coding developmental regulatory RNA; targeted mutation 2, Bernhard G Herrmann
• MGI ID: MGI:5470088
• Synonyms: Fendrr^3xpA[H]
• Gene: Fendrr Location: Chr8:121781621-121809849 bp, - strand Genetic Position: Chr8, 70.28 cM
• Alliance: Fendrr^tm2Bgh page

Mutation origin

• Mouse Generated: Earliest citation of chimera generation: J:191565
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with an FRT flanked hygro cassette and strong transcriptional stop signal via homologous recombination. (J:191565)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fendrr Mutation: 0 strains or lines available

References

• Original: J:191565 Grote P, et al., The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse. Dev Cell. 2013 Jan 28;24(2):206-14
• All: 1 reference(s)