Zfp335^tm1.1Caw
Targeted Allele Detail

Summary

• Symbol: Zfp335^tm1.1Caw
• Name: zinc finger protein 335; targeted mutation 1.1, Christopher A Walsh
• MGI ID: MGI:5470136
• Synonyms: Znf335^loxp
• Gene: Zfp335 Location: Chr2:164733802-164753677 bp, - strand Genetic Position: Chr2, 85.27 cM
• Alliance: Zfp335^tm1.1Caw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193339
• Parent Cell Line: PTL1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 1 and 2 were floxed. Flp-mediated recombination removed the FRT-flanked neo cassette inserted downstream of exon 2. (J:193339)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Zfp335 Mutation: 67 strains or lines available

References

• Original: J:193339 Yang YJ, et al., Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation. Cell. 2012 Nov 21;151(5):1097-112
• All: 1 reference(s)