Adcy7^tm1.1Pcst
Targeted Allele Detail

Summary

• Symbol: Adcy7^tm1.1Pcst
• Name: adenylate cyclase 7; targeted mutation 1.1, Paul C Sternweis
• MGI ID: MGI:5470143
• Gene: Adcy7 Location: Chr8:88999031-89056590 bp, + strand Genetic Position: Chr8, 43.06 cM
• Alliance: Adcy7^tm1.1Pcst page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:191067
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 6. An FRT-flanked neo cassette with a 3'loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the neo cassette and left exon 6 floxed. (J:191067)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adcy7 Mutation: 60 strains or lines available

References

• Original: J:191067 Jiang LI, et al., Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation. Mol Immunol. 2013 May;54(1):14-22
• All: 3 reference(s)