Gt(ROSA)26Sor^{tm1(Hoxa2)Fmr}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Hoxa2)Fmr}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Filippo M Rijli
• MGI ID: MGI:5470285
• Synonyms: ROSA26::(lox-STOP-lox)Hoxa2-IRES-EGFP, ROSA^{(lox-stop-lox)Hoxa2}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Hoxa2)Fmr} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193058
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Hoxa2)Fmr} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hoxa2 (MGI:96174)

• Mutation details: The targeting vector inserted into the locus contains a floxed neo STOP cassette, Hoxa2 cDNA, IRES and EGFP. (J:193058)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 992 strains or lines available

References

• Original: J:193058 Miguez A, et al., Opposing roles for Hoxa2 and Hoxb2 in hindbrain oligodendrocyte patterning. J Neurosci. 2012 Nov 28;32(48):17172-85
• All: 5 reference(s)