Rr24^tm1Axvi
Targeted Allele Detail

Summary

• Symbol: Rr24^tm1Axvi
• Name: regulatory region 24; targeted mutation 1, Axel Visel
• MGI ID: MGI:5470293
• Synonyms: HS586^-
• Gene: Rr24 Location: Chr13:116633778-116634790 bp, . strand Genetic Position: Chr13, Syntenic
• Alliance: Rr24^tm1Axvi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199212
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutation: Intergenic deletion
• Mutation details: Isl1 enhancer HS586, located 190 kb upstream of the gene between it and Parp8, was replaced with a loxP site flanked neomycin selection cassette which was subsequently removed by cre excision. (J:199212)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rr24 Mutation: 1 strain or line available

References

• Original: J:199212 Attanasio C, et al., Distant-Acting Craniofacial Enhancers. MGI Direct Data Submission. 2013
• All: 2 reference(s)