Rr25^tm1Axvi
Targeted Allele Detail

Summary

• Symbol: Rr25^tm1Axvi
• Name: regulatory region 25; targeted mutation 1, Axel Visel
• MGI ID: MGI:5470294
• Synonyms: HS1431^-
• Gene: Rr25 Location: Chr16:14870267-14871607 bp, . strand Genetic Position: Chr16, Syntenic
• Alliance: Rr25^tm1Axvi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:199212
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Modified regulatory region, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Snai2 enhancer HS1431, located 350 kb downstream of the gene beyond Efcab1, was replaced with a loxP site flanked neomycin selection cassette which was subsequently removed by cre excision. (J:199212)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rr25 Mutation: 1 strain or line available

References

• Original: J:199212 Attanasio C, et al., Distant-Acting Craniofacial Enhancers. MGI Direct Data Submission. 2013
• All: 2 reference(s)