Crppa^m1Ddg
Chemically induced Allele Detail

Summary

• Symbol: Crppa^m1Ddg
• Name: CDP-L-ribitol pyrophosphorylase A; mutation 1, David D Ginty
• MGI ID: MGI:5470460
• Synonyms: ISPD^L79*, Line 9445
• Gene: Crppa Location: Chr12:36431449-36739502 bp, + strand Genetic Position: Chr12, 16.84 cM
• Alliance: Crppa^m1Ddg page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a T to A mutation in Line 9445 that converts leucine 79 to a stop codon (L79) and results in an early truncation of the protein. (J:194150)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Crppa Mutation: 22 strains or lines available

References

• Original: J:194150 Wright KM, et al., Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 2012 Dec 6;76(5):931-44
• All: 3 reference(s)